• To prepare and meet out WTO Challenges pertaining to xenobiotic residues (Veterinary drugs, Pesticides and Mycotoxins)
  • To establish poison control information service
  • To obtain NABL accreditation 17025


Short-Term Objectives

  • To have a constant pharmacovigilance on Veterinary drugs (Antibiotics, growth promoters, anthelmenitics) - Drugs which have been banned for use in food animals and Drugs (Antibiotics/Antimicrobials) with MRL
    • Drugs which have been banned for use in food animals
    • Drugs (Antibiotics/Antimicrobials) with MRL
  • To generate a database on the spectrum of veterinary drugs in feed and feedstuff in Tamil Nadu.

Long-Term Objectives

  • Traceability /sources of Point contamination
  • Postmarket surveillance of approved veterinary drugs in livestock products

Quality Policy

    Pharmacovigilance Laboratory for Animal Feed and Food Safety (PLAFFS) functioning under the Directorate, Centre for Animal Health Studies (CAHS), Tamil Nadu Veterinary and Animal Sciences University (TANUVAS) is to offer the facility of testing and reporting the levels of Mycotoxins, Drug residues, Pesticides from various feeds, feed stuff and livestock farmers to prepare their products as per International Standards. The service of this laboratory is open to continuous improvement based on feedbacks and findings and through the application of the Quality Policy and Quality objectives.

    Salient Findings

    • T2 toxicosis in ostriches - 2000
    • Organophosphorous toxicity – 2001
    • Nitrate/Nitrite toxicosis in equines-2001
    • Urea toxicity in heifers-2002
    • Nitrate/Nitrite toxicosis in cattle-2004
    • Zinc phosphide toxicity in monkeys-2005
    • Hydrocyanic acid toxicity in cattle-2005
    • Nitrate/Nitrite toxicity (Weeds) in ponies and cattle-2008
    • Hydrocyanic acid toxicity (Tapioca) in cattle-2009
    • Organocarbamate – Carbofuran toxicity in elephants-2009
    • Tetradeconic acid toxicity in heifers-2010

    Test Conducted

    Analysis of animal feed and food for the presence of the following is being carried out:

    • Mycotoxins – Aflatoxin, Ochratoxin, Citrinin, Penicillic acid, T2 Toxin, Zearalenone
    • Pesticides – Organochlorine, Organophosphorous & Pyrethroids - Veterinary drugs - Banned Veterinary drugs – Chloramphenicol, Nitrofurans, Sulphanamides & Enroflaxacin
    • Drugs with permissible level – Tetracycline, Macrolide & Betalactam
    • Adulterants – Melamine/Urea
    • Pharmacotoxicological diagnosis in disease outbreak (Nitrate/Nitrite, Zinc Phosphide, Urea toxicity, Hydrocyanic Acid toxicity)

    Facilities Available/ Services Offered

    Name of the Parameter Detection method Charges (Rs.)/ Test
    For Students For Samples from Tamil Nadu For Samples from Outside Tamil Nadu
    Pesticides: Organocarbamates Organochlorine Organophosphates, Pyrethroids Gas Chromatography (GC) per Compound 800 1200 1300
    Gas Chromatography Mass Spectrometer (GCMS) per Compound 750 1200 1300
    Thin Layer Chromatography (TLC) 300 400 500
    Veterinary Drugs: Chloramphenicol , Furazolidone and metabolites Liquid Chromatography Mass Spectrometer Mass Spectrometer (LCMS/MS) per Compound 1000 1500 2000
    Chlortetracycline Ciprofloxacin Enrofloxacin Salinomycin, Tiamulin, Tylosin Thin Layer Chromatography (TLC) 300 400 500
    High Performance Liquid Chromatography (HPLC) per Compound 800 1200 1300
    Liquid Chromatography Mass Spectrometer Mass Spectrometer (LCMS/MS) per Compound 1000 1500 2000
    Aflatoxins (B1, B2, G1, G2, M1 and M2) Thin Layer Chromatography (TLC) 250 300 350
    Multi mycotoxins Thin Layer Chromatography (TLC) 400 750 1000
    High Performance Thin Layer Chromatography (HPTLC) per Compound 800 1200 1300
    800 1200 1300
    Nitrate/ Nitrite 300 600 1000
    Urea Thin Layer Chromatography (TLC) 200 250 300
    FTIR Fourier transform infrared spectroscopy per compound 150 200 300
    ICPMS Inductively coupled plasma mass spectrometry per compound 1000 1500 2000
    LCMS - Time of Flight Liquid chromatography mass spectrometer per compound 1000 1500 2000

    Quantity of Sample required for Analysis

    Sample Quantity/ Numbers
    Compounded feed / feed ingredients 250-500grams
    Bio-specimens Minimum 50grams in Saturated Saline
    Milk 100ml
    Meat 200-250grams
    Egg 6-10 Numbers
    Fodder 500grams


    • Dr. Ghadevaru Sarathchandra, Professor and Head
    • Dr. D. Raghu, Assistant Professor

    Professor and Head,
    Pharmacovigilance Laboratory for Animal Feed and Food Safety,
    Centre for Animal Health Studies, TANUVAS,
    Madhavaram Milk Colony, Chennai – 600051.
    Phone: +91-44-2555 0111
    E-mail: plaffs@tanuvas.org.in