Designation and address
Assistant Professor,
Vaccine Research Centre- Viral Vaccines, Centre for Animal Health Studies,
Madhavaram Milk Colony, Chennai 600 053.

M.S., (Microbiology and Immunology) (USA)
Ph.D. (Molecular Virology) (NUS)

Fields(s) of specialization
Majoring field : Microbiology and Immunology
Specializing field : Veterinary Virology and Vaccinology
Current Projects
Project title Role in the project Fund outlay Funding agency
Development of diagnostic tools and vaccine for Porcine circovirus 2, an emerging pathogen. Principal investigator Rs. 23 lakhs Science and Engineering Research Board (SERB), Dept. of Science and Technology (DST)
ICAR Funded Veterinary Type Culture Collection – Network project Co – Investigator at TANUVAS Unit Rs. 60 lakhs ICAR
ICAR Funded Veterinary Type Culture Collection – Network project – Tribal Sub Plan Component Co – Investigator at TANUVAS Unit Rs. 95 lakhs ICAR
Completed Projects
Project title Role in the project Fund outlay Funding agency
Efficacy of 'JR200' on Immune enhancement and Growth performance of Pacific White shrimp Litopeaneus vannamei Co-Principal investigator Rs. 2.8 Lakhs M/s. Kemin Industrial South Asia Pvt. Ltd
Recent Research Publications
  • Karuppannan AK, Ramesh A, Reddy YK, Ramesh S, Mahaprabhu R, Jaisree S, Roy P, Sridhar R, Pazhanivel N, Sakthivelan SM, Sreekumar C, Murugan M, Jaishankar S, Gopi H, Purushothaman V, Kumanan K, Babu M. Emergence of Porcine Circovirus 2 Associated Reproductive Failure in Southern India. Transbound Emerg Dis. Sep, 2014.
  • Karuppannan AK, Qiang J, Chang C C, Kwang J. A novel baculovirus vector shows efficient gene delivery of modified porcine reproductive and respiratory syndrome virus antigens and elicits specific immune response. Vaccine. 2013 November ; 31(46): 5471–5478.
  • Karuppannan AK, Wu KX, Qiang J, Chu JJ, Kwang J. Natural compounds inhibiting the replication of Porcine reproductive and respiratory syndrome virus. Antiviral Res. 2012 May;94(2):188-94.
  • Karuppannan AK, Kwang J. ORF3 of porcine circovirus 2 enhances the in vitro and in vivo spread of the of the virus. Virology. 2011 Feb 5;410(1):248-56. Meng T, Jia Q, Liu S, Karuppannan AK, Chang CC, Kwang J. Characterization and epitope mapping of monoclonal antibodies recognizing N-terminus of Rep of porcine circovirus type 2. J Virol Methods. 2010 May;165(2):222-9.
  • Karuppannan AK, Liu S, Jia Q, Selvaraj M, Kwang J. Porcine circovirus type 2 ORF3 protein competes with p53 in binding to Pirh2 and mediates the deregulation of p53 homeostasis. Virology. 2010 Mar 1;398(1):1-11.
  • Karuppannan AK, Jong MH, Lee SH, Zhu Y, Selvaraj M, Lau J, Jia Q, Kwang J. Attenuation of porcine circovirus 2 in SPF piglets by abrogation of ORF3 function. Virology. 2009 Jan 20;383(2):338-47.
Honours & Awards